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Kinetic Constants for Acetaldehyde Oxidation by Human Aldehyde Dehydrogenases
| Enzyme | KM (μM) | Vmax (min−1) | Vmax (min−1 μM−1) |
|---|---|---|---|
| ALDH1A1 | 180 | 380 | 2.1 |
| ALDH1B1 | 55 | 40 | 0.7 |
| ALDH2*1 | 0.2 | 280 | 1400 |
| ALDH2*2 | 1.4 | 20 | 14 |
Data for ALDH1A1 and ALDH2*1 from Klyosov, 1996; data for ALDH2*2 oxidation of propionaldehyde from Farrés et al., 1994 and data for ALDH1B1 from Stagos et al., 2010.
