Table 2.
Demographic and clinical characteristics of study population
| A. | ||
|---|---|---|
|
| ||
| Variable | SA (N=48) | Non-SA Comparison Group (N=166) |
| Gender (% Female) | 31.2% | 68.7% |
| Age (Mean(SD1)) | 82.6 (2.9) | 83.8 (3.8) |
| County (%) | 0.0% Adams; 43.8% Elkhart; 56.2% Holmes |
18.1% Adams; 53.6% Elkhart; 28.3% Holmes |
| 3MS (Median[Range]) | 93 [87-103] | 91 [58*-101] |
| GDS (Median[Range]) | 1 [0-4] | 3 [0-14] |
| ADL (Median[Range]) | 0 [0-1] | 1 [0-9] |
| IADL (Median[Range]) | 0 [0-1] | 1 [0-10] |
| Nagi (Median[Range]) | 0 [0-1] | 2 [0-5] |
| Rosow-Breslau (Median[Range]) | 3 [3-4] | 4 [3-6] |
| EPESE (Median[Range]) | 10 [6-12] | 7 [0-12] |
| Grip strength (dominant hand) (Median[Range]) |
23.5 [8-38] | 19 [4-45] |
| DSSI Subscales | ||
| Social interaction (Median[Range]) | 6 [2-10] | 6 [2-11] |
| Social network (Median[IQR]) | 7 [6-9.5] | 6 [5-8] |
| Instrumental support (Median[Range]) | 12 [8-12] | 12 [7-12] |
| Life satisfaction | 100% very satisfied or satisfied | 95.8% very satisfied or satisfied |
| B. | |||||
|---|---|---|---|---|---|
|
| |||||
| Pedigree | # Individuals1 | # SA | # Siblings | # Elkhart | # Holmes |
| 1 | 30 | 3 | 6 | 8 | 1 |
| 2 | 27 | 3 | 5 | 8 | 0 |
| 3 | 26 | 4 | 4 | 5 | 3 |
| 4 | 17 | 5 | 2 | 0 | 7 |
| 5 | 25 | 5 | 2 | 1 | 6 |
| 6 | 22 | 5 | 1 | 0 | 6 |
| 7 | 30 | 4 | 2 | 6 | 0 |
| 8 | 35 | 5 | 1 | 0 | 6 |
| 9 | 34 | 3 | 3 | 1 | 5 |
| 10 | 31 | 3 | 2 | 0 | 5 |
| 11 | 34 | 4 | 0 | 3 | 1 |
| 12 | 45 | 4 | 0 | 4 | 0 |
*
all individuals with 3MS < 86 were determined to be cognitively normal in detailed neuropsychological evaluation, and are thus included in the sample.
1
Total number of individuals (sampled and unsampled) in the pedigree.