. Author manuscript; available in PMC: 2014 Aug 1.

Published in final edited form as: Curr Treat Options Cardiovasc Med. 2013 Aug;15(4):387–396. doi: 10.1007/s11936-013-0252-7

Table 1. Common cardiomyopathy genes^*.

Disease	Yield of Genetic Testing	Common Disease Genes (Class)
Hypertrophic Cardiomyopathy	∼ 60 %	MYBPC3 (sarcomere) MYH7 (sarcomere) TNNT2 (sarcomere) TPM1 (sarcomere)
Dilated cardiomyopathy	∼ 35 %	TTN (sarcomere) MYH7 (sarcomere) LMNA (nuclear lamina) TNNT2 (sarcomere) RBM20 (splicesome)
Arrythmogenic (right) ventricular cardiomyopathy	∼ 50 %	PKP2 (desmosome) DSG2 (desmosome) DSP (desmosome)

Genes selected based upon frequency and data supporting their role in disease pathogenesis. Not included are genetic causes of phenocopy (e.g. Fabry and left ventricular hypertrophy)

Table 1. Common cardiomyopathy genes*.

Table 1. Common cardiomyopathy genes^*.