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Prepulse inhibition of a startle response in control mice. KO mice were impaired in the prepulse inhibition of an acoustic startle response. Two-way ANOVA showed a significant effect of genotype [F(2,49) = 5.28; ### P < .001] and prepulse intensity [F(2,49) = 56.12; P < .001]; post hoc analysis revealed significant differences at 24 dB between KO and WT (** P < .01) or Het mice (* P < .05). Values represent mean ± standard error of mean for the indicated numbers of animals.
