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. 2013 Aug 29;7:130. doi: 10.3389/fncel.2013.00130

Figure 3.

Figure 3

(A) Ictal discharges occur synchronously in entorhinal (EC) and perirhinal (PC) cortices in an in vitro brain slice treated with 4-aminopyridine (Control panel). Note that cutting the connections between entorhinal and perirhinal areas causes the occurrence of independent ictal activity in these two structures (EC/PC cut panel). (B) Two types of ictal discharge initiation can be recorded from the perirhinal cortex during bath application of 4-aminopyridine. Note that the ictal discharge shown in (a) is characterized by acceleration of the interictal events preceding its onset while that in (b) is characterized by a “slow” interictal event.