Table 5.
Relative risks and 95% confidence intervals for peripheral artery disease according to level of immune complexes (IC).
| IgG ApoB-IC | IgM ApoB-IC | ||||||||
|---|---|---|---|---|---|---|---|---|---|
|
WOMEN
| |||||||||
| Per 1 SD increase |
Tertile | Per 1 SD increase |
Tertile | ||||||
| 1 | 2 | 3 | 1 | 2 | 3 | ||||
| Range (RLU) |
272-906 | 907-1,328 | 1,329-12,372 | Range (RLU) |
23-1,142 | 1,143-2,050 | 2,051-21,500 | ||
| No. Cases | 144 | 41 | 58 | 45 | No. Cases | 144 | 49 | 52 | 53 |
| Model 1 | 1.00 (0.82-1.21) | 1.0 (ref) | 1.53 (0.96-2.44) | 1.15 (0.71-1.88) | Model 1 | 1.13 (0.95-1.33) | 1.0 (ref) | 0.78 (0.48-1.26) | 1.13 (0.71-1.80) |
| Model 2 | 0.97 (0.78-1.20) | 1.0 (ref) | 1.55 (0.94-2.55) | 1.08 (0.64-1.83) | Model 2 | 1.15 (0.96-1.38) | 1.0 (ref) | 0.82 (0.49-1.38) | 1.21 (0.74-1.98) |
| Model 3 | 0.96 (0.73-1.24) | 1.0 (ref) | 1.67 (0.96-2.93) | 0.94 (0.51-1.74) | Model 3 | 1.14 (0.92-1.41) | 1.0 (ref) | 0.78 (0.45-1.37) | 1.08 (0.61-1.91) |
|
| |||||||||
|
MEN
| |||||||||
| Per 1 SD increase |
Tertile | Per 1 SD increase |
Tertile | ||||||
| 1 | 2 | 3 | 1 | 2 | 3 | ||||
| Range (RLU) |
459-1,460 | 1,461-2,061 | 2,062-28,725 | Range (RLU) |
96-685 | 686-1,235 | 1,236-59,411 | ||
| No. Cases | 143 | 54 | 43 | 46 | No. Cases | 143 | 49 | 47 | 47 |
| Model 1 | 0.88 (0.68-1.13) | 1.0 (ref) | 0.68 (0.43-1.08) | 0.77 (0.48-1.24) | Model 1 | 1.08 (0.97-1.21) | 1.0 (ref) | 0.90 (0.57-1.43) | 0.94 (0.60-1.48) |
| Model 2 | 0.89 (0.68-1.15) | 1.0 (ref) | 0.65 (0.38-1.09) | 0.84 (0.49-1.44) | Model 2 | 1.10 (0.93-1.31) | 1.0 (ref) | 0.90 (0.54-1.52) | 0.97 (0.59-1.59) |
| Model 3 | 0.86 (0.63-1.17) | 1.0 (ref) | 0.65 (0.36-1.19) | 0.98 (0.53-1.82) | Model 3 | 1.13 (0.91-1.42) | 1.0 (ref) | 1.11 (0.63-1.97) | 0.97 (0.55-1.73) |
Model 1: adjusted for matching factors (age, race (women only), month of blood draw, fasting status, and smoking status).
Model 2: adjusted for matching factors, triglycerides, HDL-C, LDL-C, hsCRP, and HbA1c.
Model 3: adjusted for matching factors, triglycerides, HDL-C, LDL-C, hsCRP, HbA1c, parental history of MI before age 60, pack-years of smoking, physical activity, hypertension, diabetes, hypercholesterolemia, BMI, aspirin use and postmenopausal hormone use (women only).