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. 2013 Aug 29;8(8):e74666. doi: 10.1371/journal.pone.0074666

Figure 6. The knypek (glypican 6) mutant is not sensitive to Nkd1.

Figure 6

Knockdown of Nkd1 in kny -/- (C, D) or in kny +/+; +/- (G, H) does not have any affect on the kny mutant phenotype during somitogenesis (A–H) or at 1 dpf (I; n=19 kny-/-). Note the high levels of neural necrosis in nkd1 MO injected embryos at 1 dpf (I). Consistent with the lack of sensitivity, overexpression of Nkd1 has no obvious effects during early somitogenesis (J–M) or at 1 dpf (N; n=31 kny -/-). There is no change in the ratio of wild-type: mutant phenotypes.