Table 3. Incidence and power calculations for effect size in RAAS Trials.

Outcome	No. of studies	Sample Size	Incidence in Control Group n (%)	Incidence in Treatment Group n (%)	RR (95% CI)	Required RR for 80% power	Power With Current Event Rate
CV Death	8	18426	656 (7.1)	627 (6.8)	0.97 (0.78, 1.21)	0.86	8%
All-cause Mortality	20	32843	1700 (10.4)	1704 (10.4)	0.99 (0.92, 1.08)	0.91	5%

Abbreviations: RAAS =  Renin angiotensin aldosterone system; CV =  cardiovascular; RR =  relative risk.