Table 1. Period of normoglycemia after subcutaneous transplantation of PSI in diabetic immunocompetent mice.
Group | n | Days of normoglycemia |
---|---|---|
PSI + 106 BM-MSCsalo | 7 | 4.2 ± 1.07a |
PSI + 2x 105 BM-MSCsallo and 2 x 105 fibroblastsauto | 5 | 7.2 ± 0.49b |
PSI + 4x 105 BM-MSCsallo and 4 x 105 fibroblastsauto | 5 | 11.6 ± 3.04 |
PSI + 106 BM-MSCsallo and 106 fibroblastsauto | 7 | 18.4 ± 3.86 |
a p<0.05 versus all groups.
b p<0.05 versus PSI + 106 BM-MSCsallo and 106 fibroblastsauto
ANOVA of data followed by the Scheffé post hoc test
All results are expressed as mean ± SEM.
PSI, plasma-based scaffold containing xenogenic islets; BM-MSCsallo, allogenic bone marrow-mesenchymal stem cells; fibroblastsauto, autologous skin fibroblasts