Table 4. Correlations among empirical measures of insulin sensitivity and model-derived insulin sensitivity indices.

	HOMA-IS	ISIcomp	MCRrest	OGIS	ISBREDA	ISNAIF	ISDMMO	ISCOMO	kxgi
HOMA-IS	1	0.87**	0.50**	0.54**	0.56 **	0.45**	0.31*	0.016 NS	0.49**
ISIcomp	0.87**	1	0.60**	0.77**	0.87**	0.71**	0.62**	0.02 NS	0.79**
MCRrest	0.50**	0.60**	1	0.69**	0.65**	0.71**	0.33*	0.084 NS	0.56**
OGIS	0.54**	0.77**	0.69**	1	0.75**	0.83**	0.53**	0.080 NS	0.72**
ISBREDA	0.56**	0.87**	0.65**	0.75**	1	0.81**	0.77**	−0.02 NS	0.90**
ISNAIF	0.45**	0.71**	0.71**	0.83**	0.81**	1	0.54**	0.015 NS	0.72**
ISDMMO	0.28*	0.51**	0.33*	0.48**	0.69**	0.58**	1	−0.07 NS	0.63**
ISCOMO	0.016 NS	0.02 NS	0.084 NS	0.080**	−0.02 NS	0.015 NS	−0.07 NS	1	−0.05 NS
kxgi	0.49**	0.79**	0.56**	0.72**	0.90**	0.72**	0.70**	−0.05 NS	1

Asterisks indicate significance of the correlations: * P<0.01, **P<0.001, NS Not Significant.

HOMA-IS: Homeostasis Model Assessment.

ISIcomp: Insulin Sensitivity Index Composite.

MCRrest: glucose Metabolic Clearance Rate.

OGIS: Oral Glucose Insulin Sensitivity index as estimated in [6].

IS_BREDA: Insulin Sensitivity index as derived in [9].

IS_NAIF: Insulin Sensitivity index computed as the inverse of the mean of the observed glycemias during the OGTT.

IS_DMMO: Insulin Sensitivity index as derived from the Dalla Man model [10].

IS_COMO: Insulin Sensitivity index as derived from the Salinari model [13].

k_xgi: Insulin Sensitivity index as derived from the proposed SIMO model.