Table 5. Insulin sensitivity indices estimates by group.
kxgi [min−1 pM−1] | NGT | IFG | T2DM | IFG+IGT | IGT |
Mean | 8.62E-05 | 5.30E-05 | 2.38E-05 | 2.38E-05 | 2.09E-05 |
Standard Deviation | 9.36E-05 | 5.18E-05 | 2.09E-05 | 2.28E-05 | 1.95E-05 |
group mean ±SD | 2.27E-05±2.04E-05 | ||||
kxgi trimmed [min−1 pM−1] | NGT | IFG | T2DM | IFG+IGT | IGT |
Mean | 5.70E-05 | 4.12E-05 | 2.00E-05 | 1.90E-05 | 1.69E-05 |
SD | 2.70E-05 | 1.70E-05 | 8.18E-06 | 1.29E-05 | 6.04E-06 |
group mean ± SD | 5.13E-05±2.47E-05 | 1.86E-05±8.86E-06 | |||
kxgi interpolated [min−1 pM−1] | NGT | IFG | IFG-IGT | IGT | T2DM |
Mean | 7.10E-05 | 5.88E-05 | 2.61E-05 | 2.45E-05 | 1.91E-05 |
Standard Deviation | 6.98E-05 | 5.37E-05 | 2.23E-05 | 1.58E-05 | 1.39E-05 |
group mean ± SD | 2.31E-05±1.71E-05 | ||||
kxgi interpolated trimmed [min−1 pM−1] | NGT | IFG | IGT | IFG+IGT | T2DM |
Mean | 5.35E-05 | 4.20E-05 | 2.13E-05 | 1.95E-05 | 1.78E-05 |
Standard Deviation | 2.05E-05 | 1.54E-05 | 5.69E-06 | 1.48E-05 | 5.66E-06 |
group mean±SD | 4.94E-05±1.93E-05 | 1.96E-05±9.46E-6 | |||
ISCOMO [min−1 pM−1] | IFG | IGT | NGT | IFG+IGT | T2DM |
Mean | 1.06E-02 | 6.07E-03 | 3.31E-04 | 2.32E-04 | 2.71E-05 |
Standard Deviation | 2.66E-02 | 1.85E-02 | 1.14E-03 | 5.47E-04 | 5.83E-05 |
ISCOMO trimmed [min−1 pM−1] | IFG | IGT | NGT | IFG+IGT | T2DM |
Mean | 4.17E-04 | 9.04E-05 | 8.94E-05 | 5.42E-05 | 2.78E-06 |
Standard Deviation | 9.84E-04 | 5.00E-05 | 5.35E-05 | 4.88E-05 | 6.25E-06 |
ISDMMO [min−1 pM−1] | NGT | IFG | T2DM | IGT | IFG-IGT |
Mean | 3.91E-03 | 2.27E-03 | 1.32E-03 | 8.96E-04 | 3.62E-04 |
Standard Deviation | 9.68E-03 | 4.49E-03 | 2.16E-03 | 1.99E-03 | 9.40E-04 |
ISDMMO trimmed [min−1 pM−1] | T2DM | NGT | IFG | IGT | IFG-IGT |
Mean | 6.59E-04 | 3.80E-04 | 2.59E-04 | 2.58E-04 | 6.54E-05 |
Standard Deviation | 7.99E-04 | 4.90E-04 | 1.93E-04 | 4.75E-04 | 7.65E-05 |
ISDMMO: Insulin Sensitivity index as derived from the Dalla Man model [10].
ISCOMO: Insulin Sensitivity index as derived from the Salinari model [13].
kxgi: Insulin Sensitivity index as derived from the proposed SIMO model.
The term “trimmed” was used to identify the subgroup consisting of values of the insulin sensitivity index between the 20th and 80th percentile.
The term “interpolated” coupled with the kxgi index refers to parameter estimate values obtained when observed insulin concentrations are interpolated rather than fitted.