Table 1. Clinical features of EAE in the administration of Vehicle or SM934.
| Preventive treatment (n = 30) | Therapeutical treatment from onset (n = 30) | Therapeutical treatment from peak (n = 30) | ||||||
| Group | Incidence %) | Average day of onset | Average day of peak | Mean maximal score | Average day of peak | Mean maximal score | Average day of peak | Mean maximal score |
| Vehicle | 100% | 13.5±0.33 | 17.8±0.42 | 3.37±0.20 | 18.3±0.61 | 3.57±0.14 | 19.0±0.77 | 3.3±0.17 |
| SM934 | 63% | 20.3±1.48*** | 22.4±1.20** | 2.2±0.34* | 20.9±0.74** | 2.77±0.18** | 18.4±0.47 | 3.1±0.23 |
Data were expressed as mean ± SEM, from three independent experiments,
P <0.05, ** P < 0.01, ***p<0.001 versus vehicle.