Table 2. The higher integrin α5β1 expression in the H. pylori-infected patients with the serum pepsinogen I/II ratio <6.0.
| Groups | PG I/II <6.0 (n = 37) | PG I/II ≥6.0 (n = 135) | P |
| Mean agea (yr) | 63.8 | 55.6 | 0.002 |
| Femaleb % (n) | 48.6 (18/37) | 40.0 (54/135) | 0.345 |
| Supranuclear or apical expression of integrin α5β1b %(n) | P value; OR [95% CI] | ||
| Antrum | 59.5 (22/37) | 40.0 (54/135) | 0.035; 2.20 [1.50–4.62] |
| Corpus | 48.6 (18/37) | 28.1 (38/135) | 0.018; 2.42 [1.15–5.10] |
| The modified intensity of integrin α5β1c | (median, [25th ∼75th IQR]) | ||
| Antrum | 3.0 [2.0 ∼4.0] | 2.0 [2.0 ∼4.0] | 0.094 |
| Corpus | 2.0 [2.0 ∼4.0] | 2.0 [1.0 ∼4.0] | 0.029 |
a
by Student’s t test.
b
by Chi-square test.
c
by Mann-Whitney test. PGI, pepsinogen I; PGII, pepsinogen II. PG I/II: indicates the ratio of pepsinogen I/pepsinogen II. OR [95% CI]: odd ratio [95% confidence interval].