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. 2013 Aug 29;8(8):e73116. doi: 10.1371/journal.pone.0073116

Figure 4. Sequence analysis of CCR6-using HIV-2MIR and SIVsmE660 isolates.

Figure 4

The amino acid alignment of the C2-V3 region of the HIV-2MIR-CCR6 variant has been made with parental HIV-2MIR-CCR5 variant. Similarly, genetic divergence of the V1-V3 region of the SIVsmE660-R6 was determined by the pair-wise comparison to its R5-variant. (A) Each pair of R6 and R5 variants has been aligned. Dots indicate identity and letters represent substitutions in the adapted variants relative to the parental isolate. The positions of the common amino acid changes were marked by ♦. The V3 domain was indicated by dashes. (B) Amino acid sequences of two clones of R6-variant were aligned with two clones of R5-variant in the V1, V2 and V3 domains. The regions equivalent to the V1, V2 and V3 of SIV are indicated by dashes. Dots indicate the identity with the parental isolate; letters represent differences in the adapted variants. The positions of common amino acid changes were marked by ▲.