Table 3. Prevalence of drug-resistance mutations between the therapy-naïve (n = 94) and ART-failure population (n = 515) in the Yunnan province in 2010–2011.
Protease inhibitor | Nucleoside reverse transcriptase inhibitor | Non-nucleoside reverse transcriptase inhibitor | ||||||
Mutations | Frequency (%) | Mutations | Frequency (%) | Mutations | Frequency (%) | |||
Naïve (n = 94) | ART-failure (n = 515) | Naïve (n = 94) | ART-failure (n = 515) | Naïve (n = 94) | ART-failure (n = 515) | |||
L10F | 0.0 | 0.6 | M41L | 0.0 | 3.7 | A98G | 0.0 | 2.1 |
V11I | 0.0 | 1.0 | K65R | 0.0 | 0.2 | K101Q | 0.0 | 1.4 |
L23I | 0.0 | 0.2 | D67TG | 0.0 | 0.8 | K101E | 0.0 | 3.7 |
D30N | 1.1 | 0.0 | D67N | 0.0 | 3.9 | K103N | 0.0 | 19.2 |
L33F | 0.0 | 1.2 | T69D | 0.0 | 1.0 | K103R | 0.0 | 2.9 |
M46IL | 0.0 | 0.8 | T69ins | 1.1 | 0.0 | V106A | 0.0 | 22.1 |
Q58E | 0.0 | 1.0 | K70R | 0.0 | 4.5 | V106M | 0.0 | 2.9 |
L76V | 0.0 | 0.4 | L74I | 0.0 | 0.2 | V108I | 0.0 | 2.9 |
V82A | 0.0 | 0.4 | V75TAM | 0.0 | 1.6 | E138GQ | 0.0 | 1.0 |
V82F | 0.0 | 0.2 | F116Y | 0.0 | 0.2 | Y181V | 0.0 | 0.6 |
I84V | 0.0 | 0.2 | Q151M | 0.0 | 0.6 | Y181C | 0.0 | 11.8 |
N88D | 0.0 | 0.2 | M184VI | 0.0 | 28.2 | Y188L | 0.0 | 0.8 |
L90M | 1.1 | 0.0 | L210W | 0.0 | 1.2 | Y188C | 0.0 | 0.8 |
T215Y | 0.0 | 2.7 | Y188F | 0.0 | 0.2 | |||
T215F | 0.0 | 4.1 | G190S | 0.0 | 0.6 | |||
K219Q/E | 0.0 | 5.1 | G190A | 0.0 | 12.4 | |||
P225H | 0.0 | 2.9 | ||||||
F227L | 0.0 | 1.2 | ||||||
M230L | 0.0 | 1.9 | ||||||
K238T | 0.0 | 1.0 |