Figure 2. Cytokine production from the lung homogenates of C. pneumoniae infected mice.
C57BL/6 (B6) or B6.C3H-sst1 congenic mice were infected with C. pneumoniae (Cp) as described in the Methods. At day 3 and day 6 post infection, mice were euthanized and lung homogenates prepared for detection of a panel of inflammatory cytokines and chemokines. Shown above are a subset of the cytokines assayed: (A) IL-6, (B) IL-1β, (C) IL-10, (D) IFN-β, (E) IFN-γ and (F) MCP-1. Each data point represents one mouse, and the horizontal bar represents the mean. Significance: *, p<0.05; **, p≤0.01; ***, p≤0.001 infected C57BL/6 vs. B6.C3H-sst1 mice. The result is representative of two independent experiments.