Table 2.
Knockout | Tissue | Cytokines Dysregulated | Ref |
---|---|---|---|
SOCS3−/− | All | LIF | 69 |
cKO (vav-cre) | Haematapoietic | G-CSF/IL-6 | 22,23 |
cKO (LysM-cre) | Macrophage | IL-6 | 92 |
cKO (Alb-cre) | Liver | IL-6 | 57 |
cKO (Nes-cre) | Brain | Leptin | 44,52 |
cKO (MBP-cre) | oligodendrocytes | LIF | 28 |
cKO (Lck-cre) | T-cells | IL-6 | 46 |
cKO (Ad-cre*) | Retina | CNTF | 75 |
Denotes adenoviral-cre delivery