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Operating characteristics of the design generalized from Whitehead et al. (2008) without any sample size reestimation (NW = NM = 80).
| Scenario | Women | Men | ||||
|---|---|---|---|---|---|---|
| P(efficacy) (ΔpW > 0) | P(futility) (ΔpW < 0. 2) | P(conclusive) (W overall) | P(efficacy) (ΔpM > 0) | P(futility) (ΔpM < 0. 2) | P(conclusive) (M overall) | |
| 1 | 1.00 | 0.00 | 1.00 | 0.91 | 0.11 | 1.00 |
| 2 | 0.92 | 0.12 | 1.00 | 0.11 | 0.92 | 1.00 |
| 3 | 0.09 | 0.94 | 1.00 | 0.12 | 0.90 | 1.00 |
| 4 | 0.51 | 0.56 | 1.00 | 0.58 | 0.59 | 1.00 |
| 5 | 0.53 | 0.53 | 1.00 | 1.00 | 0.00 | 1.00 |
| 6 | 1.00 | 0.00 | 1.00 | 0.00 | 1.00 | 1.00 |
