Table 1.
Effects of oxATP or knockdown P2X7 on systolic blood pressure, diastolic blood pressure, heart rate
| Group | Systolic blood pressure (mmHg) | Diastolic blood pressure (mmHg) | Heart rate (/min) |
|---|---|---|---|
| A | |||
| Sham (n = 8) | 110.04 ± 9.53 | 72.35 ± 7.35 | 341.88 ± 35.43 |
| con+oxATP (n = 8) | 108. 65 ± 10.72 | 73.43 ± 8.56 | 334.70 ± 36.90 |
| MI (n = 8) | 128.00 ± 13.54* | 91.06 ± 9.14* | 426.72 ± 44.21* |
| MI+oxATP (n = 8) | 111.16 ± 10.87 | 73.65 ± 9.87 | 398.72 ± 39.81** |
| B | |||
| Sham (n = 8) | 110.17 ± 10.56 | 76.66 ± 7.14 | 352.24 ± 21.38 |
| MI (n = 8) | 133.40 ± 8.37*** | 97.89 ± 8.23*** | 438.42 ± 30.53*** |
| MI+P2X7 siRNA (n = 8) | 111.16 ± 7.62 | 77.27 ± 6.98 | 349.78 ± 25.74 |
| MI+Scramble siRNA (n = 8) | 131.93 ± 10.65*** | 100.81 ± 7.35*** | 428.20 ± 28.89*** |
Data are presented as means ± SE
*p < 0.05, compared with sham group, oxATP control group, and myocardial ischemic rats treated with oxATP group; **p < 0.05, compared with sham and oxATP control group; ***p < 0.05, compared with sham group and myocardial ischemic rats treated with P2X7 siRNA group.