Table 3.
Effect of oral administration of isolated fraction (DV-1) on plasma glucose concentration, cholesterol, triglyceride, and HDL for 21 days
| Treatment | Fasting plasma glucose (mg/dl) | Cholesterol (mg/dl) | Triglyceride (mg/dl) | HDL (mg/dl) | ||
|---|---|---|---|---|---|---|
| 0 day | 10 day | 21 day | ||||
| Normal control | 64.8 ± 7.9 | 91.9 ± 3.2 | 89.3 ± 6.9 | 93.6 ± 4.3 | 71.6 ± 5.6 | 42.2 ± 1.9 |
| Diabetes alone | 249.7 ± 4.8 | 207.6 ± 8.5 | 195.7 ± 5.4 | 84.5 ± 3.4 | 110.6 ± 7.8 | 40.3 ± 2.1 |
| Diabetes + DV-1 (100 mg/kg) | 252.6 ± 4.1 | 186.3 ± 2.5* | 161.2 ± 7.1* | 87.6 ± 2.6 | 64.6 ± 7.5* | 46.7 ± 2.3* |
| Diabetes + Metformin (50 mg/kg) | 243.6 ± 2.8 | 178.8 ± 4.5* | 156.8 ± 6.8* | 84.3 ± 4.8 | 95.6 ± 5.6 | 47.6 ± 1.3* |
Data are expressed as mean ± SEM. n = 6 rats per group. *p < 0.05, compared to diabetic control group.