TABLE 1.
Sugar modifications identified on N1(6–15) by tandem mass spectrometry of chymotryptic peptides
| Peptide sequence | Notch residues | Modification | Location |
|---|---|---|---|
| YCECPHGRTGLL | 358–369 | Fucose | EGF9 |
| TGPRCEIDVNECVSNPCQNDATCLDQIGEF | 445–474 | Fucose | EGF12 |
| GSCKDGVATFTCL | 578–590 | Fucose | EGF15 |
| CTEDVDECQLMPNACQNGGTCHNTHGGY | 292–319 | Fucose | EGF8 |
| HGATCHDRVASF | 346–357 | Fucose | EGF9 |
| TGTHCEVDIDECDPDPCHY | 559–577 | HexNAc | EGF14 |
| TCVCTEGYTGTHCEVDIDECDPDPCHY | 551–577 | HexNAc | EGF14 |
| GSFECQCLQGY | 434–444 | Hexose | EGF11 |
| DVDECASTPCKDGAKCL | 528–544 | Xyl-Xyl-hexose | EGF14 |