Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Aug 30;7:138. doi: 10.3389/fncel.2013.00138

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Toader, Forte, Orlando, Ferrea, Raimondi, Baldelli, Benfenati and Medrihan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The hilar mossy cell phenotype of pre-symptomatic Syn II^−/− mice is maintained in adult symptomatic Syn II^−/− mice. (A) Representative mEPSC traces (A) and cumulative distributions (B) of their amplitude and frequency from 4 to 6 months old WT (black) and Syn II^−/− (red) mossy cells; ^***p < 0.001, Kolmogorov–Smirnov test. (C) Mean (±s.e.m.) rise-time (10–90%) and mono-exponential τ of decay of mEPSCs from 4–6 months old WT (black bars) and Syn II^−/− (red bars) neurons. (D) Representative traces of current-clamp recordings from hilar mossy neurons in acute slices of WT (black) and symptomatic Syn II^−/− (red) mice. (E) Frequency of APs plotted as a function of the injected current for both genotypes. (F) Mean (±s.e.m.) rheobase and input resistance; ^*p < 0.05, two-tailed unpaired Student's t-test.