Table 1. Activation parameters for Mannich reaction of imine and fluorinated ketoester catalyzed by thiourea C at different temperatures.

Entry	T (K)	kobs (M−1s−1)	k (M−2s−1)	ee (%)
1	283	(7.9 ± 0.04) × 10−3	0.66 ± 0.0033	93
2	293	(7.2 ± 0.05) × 10−3	0.60 ± 0.0042	93
3	303	(6.1 ± 0.08) × 10−3	0.51 ± 0.0067	93
4	313	(5.6 ± 0.09) × 10−3	0.47 ± 0.0075	93