Table 1.

Genes differentially methylated between the FaDu and FaDu-HIF1a cell lines.

Category	Gene name
Metastasis related genes	LMNA, VANGL, RGS4, MALL, DLX2, TNS1, WNT7A, CXCL9, EREG, MAD2L, KIF2A, SPRY4, FOXO3, SEMA3C, ADAM9, SNAI2, FABP5, EDG2, CXCL12, IFIT2, SLK, FOSL1, MMP7, PVRL1, JAM2, JAM3, VDR, JUB, LGALS3, HIF1a, LASP1, CCR7, HOXB2, ITGA3, SOX9, SMAD4, SNF1LK, MID1, KLF8, MSN
Tumor Suppressor genes	RPRM, PTPRG, SULF1, MTAP, RASEF, SYK, PDCD4, IFT88, INTS6, COPS2, ADAMTS18, CDH13, STARD8
Tumorigenesis genes (oncogene, overexpression, prognosis markers)	JUNB, ERG(TF), PBX1(TF), REL, ATF2(TF), H2AFZ, CARD6, SPZ1 (TF), DRD1, ICK, SDK1(FRA7B), DMD, ETV1, JAZF1, DBF4, TRPV6, DEFB1, STC1, HNF4G, RAD21, MYC, DOCK8, RLN1,2, MPDZ, KLF9, PTGS1, TSG101, CRY1, GPC5, HBLD1, UBE2Q2, SS18, KLK2,3, MAGEH1, MAGEA4, LUZP4
Apoptosis related genes	BHLHB, PDCD4, PDCD5, BAX. GZMH, FEM1B
Hypoxia response genes	JMJD1A, EIF2AK3, IGFBP5, FOXP1, CXCL9, CTGF, NKX3-1, TXN, HIF1a, NOS2A, KLF2
Cell cycle genes	MAD2L, CCNG1, DBF4, SMC2, VRK1, RASGR, PCNA