Table 3.
Mean (SD) and median (25th–75th percentiles) EORTC QLQ-C30 scores of German melanoma patients at baseline (Q1; OVIS I) and follow-up (Q2; OVIS II) and the German reference population.
| German Men* | OVIS I-Men [n = 208] | OVIS II-Men [n = 208] | German Women* | OVIS I-Women [n = 242] | OVIS II-Women [n = 242] | |
|---|---|---|---|---|---|---|
| Global health status/QoL | 66.7 | 75.2 (21.8) 83.3 (66.7–91.7) |
76.8 (21.3) 83.3 (66.7–91.7) |
66.1 | 73.9 (22.7) 83.3 (58.3–91.7) |
74.7 (22.2) 83.3 (58.3–100) |
| Physical functioning (revised) | 86.0 | 93.0 (17.1) 100 (100–100) |
91.9 (20) 100 (100–100) |
85.3 | 92.3 (17.2) 100 (100–100) |
91.8 (18.9) 100 (100–100) |
| Role functioning (revised) | 84.1 | 87.4 (24.4) 100 (83.3–100) |
87.0 (25.0) 100 (83.3–100) |
83.3 | 86.7 (24.3) 100 (83.3–100) |
85.1 (26.2) 100 (66.7–100) |
| Emotional functioning | 78.6 | 79.4 (24.4) 91.7 (66.7–100) |
79.8 (23.0) 83.3 (66.7–100) |
74.2 | 73.6 (26.7) 83.3 (58.3–100) |
72.5 (29.0) 83.3 (58.3–100) |
| Cognitive functioning | 87.6 | 89.4 (19.6) 100 (83.3–100) |
86.8 (21.0) 100 (83.3–100) |
87.4 | 88.8 (20.8) 100 (83.3–100) |
87.9 (21.0) 100 (83.3–100) |
| Social functioning | 87.0 | 87.7 (23.4) 100 (83.3–100) |
90 (21.9) 100 (100–100) |
87.7 | 85.0 (25.8) 100 (83.3–100) |
86.7 (23.0) 100 (83.3–100) |
| Fatigue | 12.7 | 16.3 (24.7) 0 (0–22.2) |
18.6 (25.4) 11.1 (0–22.2) |
20.0 | 20.4 (27.3) 11.1 (0–33.3) |
22.7 (27.5) 11.1 (0–33.3) |
| Nausea and vomiting | 1.9 | 1.2 (5.2) 0 (0–0) |
1.8 (6.8) 0 (0–0) |
3.4 | 2.8 (10.6) 0 (0–0) |
2.5 (10.5) 0 (0–0) |
| Pain | 16.8 | 12.8 (23.8) 0 (0–16.7) |
11.4 (21.9) 0 (0–16.7) |
18.1 | 17.0 (28.5) 0 (0–33.3) |
17.6 (28.1) 0 (0–33.3) |
| Dyspnoea | 9.8 | 12.7 (27.0) 0 (0–0) |
13.5 (26.4) 0 (0–0) |
9.7 | 11.9 (24.6) 0 (0–0) |
13.5 (26.6) 0 (0–33.3) |
| Insomnia | 16.4 | 18.1 (30) 0 (0–33.3) |
21.7 (31.3) 0 (0–33.3) |
20.5 | 23.5 (33.4) 0 (0–33.3) |
25.1 (32.9) 0 (0–33.3) |
| Appetite loss | 4.9 | 3.9 (14.6) 0 (0–0) |
5.6 (16.6) 0 (0–0) |
6.2 | 5.2 (16.9) 0 (0–0) |
5.7 (18.1) 0 (0–0) |
| Constipation | 3.5 | 6.0 (17.6) 0 (0–0) |
7.8 (21.0) 0 (0–0) |
4.5 | 4.8 (15.1) 0 (0–0) |
8.1 (21.7) 0 (0–0) |
| Diarrhea | 2.5 | 5.6 (17.2) 0 (0–0) |
6.2 (16.4) 0 (0–0) |
2.8 | 7.1 (19.4) 0 (0–0) |
6.8 (18.7) 0 (0–0) |
| Financial difficulties | 7.3 | 6.2 (17.6) 0 (0–0) |
7.7 (19.9) 0 (0–0) |
6.6 | 5.1 (16.1) 0 (0–0) |
8.4 (21.7) 0 (0–0) |
*
The age structure of the German reference population was adjusted to the age structure of the OVIS patients at baseline (‘direct age-standardization’ as suggested by Hjermstad et al. [17]). Therefore, only mean values are presented.