Figure 3. Between group differences in DMN for MCI patients and Healthy controls (HC).

Panel (A) shows t-maps obtained when comparing MCI and HC. T-test comparisons reveal statistically significant increased levels of intrinsic connectivity in the Posterior Cingulated Cortex (PCC) and left Inferior Parietal Lobe (left IPL) in the MCI group. Panel (B) shows t-maps obtained when comparing MCI-AD converted and HC. Between group comparisons show significant increased values of intrinsic connectivity in the right Inferior Parietal Lobe (right IPL) in MCI-AD converted group. Functional maps shown in A and B are Bonferroni corrected (p < 0.05) and overimposed on a Talairach template.