Fig. 5. Induction of CD4⁺CD25⁺Foxp3⁻ Teff apoptosis and inhibition of IFN-γ secretion by HCV⁺ hepatocytes.

A) Annexin V expression on CD4⁺CD25⁺Foxp3⁻ Teffs by incubation of CD4⁺ T cells with HCV^+/− hepatocytes. The data are reproducible in three independent experiments, **P<0.01. B) IFN-γ secretion in the supernantant of CD4⁺ T cells co-cultured with HCV^+/− Huh-7 cells, measured by cytometric bead array in three independent experiments. *P<0.05.