Fig. 4.

Effects of various tested compounds on the proliferation of COX-2 positive (MAD-MB-231) cell line. Cells were exposed for 48 h to different concentrations (0.001, 0.01, 0.1, 1 mM) of compounds as indicated. Untreated cells incubated in the presence of vehicle (1% DMSO) and were used as negative control. Doxorubicin (0.1 mM) was used as positive control. For statistical significance one-way ANOVA was used to analyze the differences between each sample and negative control (*P<0.05, **P<0.01).