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Effect of TrxR1 status on acrolein-induced phase II responses. Selenite-supplemented (A) or TXNRD1 siRNA transfected (B) HBE1 cells were treated with acrolein and expression of HO-1, NQO-1, and TrxR1 were analyzed after 8 h by Western blot. Quantified HO-1 band densities relative to β-actin are presented as mean±SEM (n=4) (C, D).
