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. 2013 Feb 8;1(1):244–257. doi: 10.1016/j.redox.2013.01.014

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© 2013 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig. 16 — The proposed reaction mechanism of Michael addition reactions between Michael acceptors and cysteine sulfhydryl groups in Keap1. [From: Magesh, S., et al. Small molecule modulators of Keap1–Nrf2–ARE pathway as potential preventive and therapeutic agents. Medicinal Research Reviews32:687–726; 2012.].