Table 5.

RT-PCR expression of genes related to redox regulation in brain tissue at P1 and P7 in mice pups born under hypoxic conditions (O14; FiO₂=14%; n=3) or under normoxic conditions (O21; FiO₂=21%; n=4). The table shows fold expression of Glucose 6 phosphate dehydrogenase (g6pdx), phosphogluconate dehydrogenase (pgd), malic enzyme 1 (me1), glutathione reductase (gsr), thioredoxin reductase 1 (txnrd1), NADPH:quinone oxidoreductase 1 (nqo1) and sulfiredoxin 1(srxn1). Comparisons between groups were made using the Wilcoxon rank sum test. Glyceraldehyde 3-phosphate dehydrogenase (gapdh) was used as housekeeping gene.

Fold change	g6pdx	pgd	me1	gsr	txnrd1	nqo1	srxn1
O21_1 day	1.04±0.35	1.02±0.23	1.01±0.17	1.02±0.24	1.02±0.25	1.03±0.29	1.04±0.33
O14_1 day	1.03±0.29	1.30±0.63	0.99±0.38	1.01±0.47	0.92±0.39	0.86±0.53	0.89±0.34
O21_7 days	0.60±0.14	0.75±0.28	0.57±0.18	0.64±0.11	0.55±0.11	0.44±0.14	1.95±0.31
O14_7 days	0.52±0.15	0.73±0.24	0.88±0.15	0.42±0.03#	0.68±0.49	0.49±0.22	1.79±0.37

^#p<0.05.

^**p<0.01 vs. O21 group at P1.