Figure 2.
Soluble endoglin (sEng) is a better predictor of the presence of pulmonary arterial hypertension than N-terminal brain natriuretic peptide (NT-proBNP). Receiver operator characteristic curves for sEng, soluble VEGF receptor-1 (sVEGFR1), C-reactive protein (CRP), and osteoprotegerin (OPG) are depicted in relationship to NT-proBNP as a reference biomarker. Areas under the curve (AUC ± SEM) were determined for sEng (0.824 ± 0.033), sVEGFR1 (0.785 ± 0.045), CRP (0.769 ± 0.042), NT-proBNP (0.714 ± 0.051), and OPG (0.584 ± 0.049), *P<0.05 versus NT-proBNP; #P<0.05 versus OPG.