Table 7.
Predictors of receiving uninterrupted DAPT.
| Univariable Analysis | Multivariable Analysis | |||||
|---|---|---|---|---|---|---|
| Variable | Chi square |
OR (95% CI) |
p value | Chi square |
OR (95% CI) |
p value |
| Age (per 1 year increase) | 84.2 | 0.99 (0.98, 0.99) |
< 0.0001 | 27.0 | 0.99 (0.98, 0.99) |
< 0.0001 |
| Diabetes | 55.7 | 1.59 (1.41, 1.79) |
< 0.0001 | 25.6 | 1.43 (1.25, 1.66) |
< 0.0001 |
| Number of medications at discharge (per additional medication) |
25.5 | 1.10 (1.05, 1.12) |
< 0.0001 | 1.1 | 1.02 (0.98, 1.07) |
0.28 |
| Use of Coumadin at discharge | 14.8 | 0.61 (0.48, 0.79) |
< 0.0001 | 14.5 | 0.60 (0.46, 0.78) |
0.0001 |
| Prior myocardial Infarction | 24.5 | 1.45 (1.23, 1.69) |
< 0.0001 | 15.9 | 1.36 (1.17, 1.58) |
< 0.0001 |
| Multivessel coronary artery disease | 41.4 | 1.39 (1.22, 1.54) |
< 0.0001 | 10.0 | 1.23 (1.08, 1.40) |
0.0016 |
| History of prior CABG | 13.3 | 1.37 (1.15, 1.64) |
0.0003 | 2.0 | 1.14 (0.94, 1.39) |
0.16 |
| Stenting of left main coronary artery | 9.1 | 1.79 (1.22, 2.70) |
0.003 | 5.9 | 1.65 (1.10, 2.54) |
0.015 |
| Hyperlipidemia | 8.4 | 1.32 (1.10, 1.56) |
0.003 | 1.6 | 1.13 (0.94, 1.35) |
0.21 |
| Male gender | 7.7 | 1.19 (1.05, 1.33) |
0.005 | 3.3 | 1.13 (0.99, 1.28) |
0.069 |
| Hypertension | 10.29 | 1.33 (1.12, 1.59) |
0.012 | 4.0 | 1.21 (1.00, 1.45) |
0.047 |
| Total index lesion length (per 1 mm) | 6.01 | 1.01 (1.00, 1.01) |
0.015 | 0.4 | 1.00 (1.00, 1.01) |
0.052 |
| Number of lesions undergoing intervention at index PCI (per lesion) |
5.9 | 1.11 (1.02, 1.22) |
0.018 | 0.2 | 1.03 (0.90, 1.17) |
0.62 |
| Presentation with unstable coronary syndrome or AMI (versus stable presentation) |
4.68 | 1.14 (1.01, 1.28) |
0.031 | 4.5 | 1.14 (1.01, 1.28) |
0.034 |
| Chronic renal impairment | 4.7 | 1.23 (1.02, 1.52) |
0.032 | 1.4 | 1.13 (0.92, 1.38) |
0.24 |
| Prior cerebrovascular accident | 2.63 | 1.23 (0.96, 1.61) |
0.10 | 1.8 | 1.20 (0.92, 1.57) |
0.1823 |
| Current smoking | 2.3 | 1.12 (0.97, 1.32) |
0.13 | - | - | - |
| Left ventricular ejection fraction (per 1 % increase) |
2.14 | 1.00 (1.00, 1.00) |
0.14 | - | - | - |
| Hemoglobin concentration pre-PCI (per 1 g/dL increase) |
2.08 | 0.98 (0.94, 1.01) |
0.14 | - | - | - |
| Peripheral vascular disease | 1.4 | 1.15 (0.92, 1.43) |
0.24 | - | - | - |
| Dialysis | 1.04 | 1.22 (0.84, 1.79) |
0.31 | - | - | - |
Abbreviations not previously defined: OR, odds ratio.