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Mitochondrial genome. The mitochondrial genome exists as a closed, double-stranded circular genome of 16,569 base-pairs in length. This encodes for 37 genes, including 13 polypeptide components of the electron transport system. This figure highlights some of the mutations associated with mitochondrial disease including m.3243A>G, m.8344A>G, and the site of the common mtDNA deletion.
