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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: J Magn Reson Imaging. 2012 Oct 23;37(1):138–145. doi: 10.1002/jmri.23786

Table 4.

Diagnostic accuracy of normalized MTR and DCE data.

Cut-off Sensitivity
(95% CI)		 Specificity
(95% CI)		 AUC
(95% CI)		 Accuracy
(%)		 Cross-
validation
(%)
NMTR 0.56 79.3
(59.7, 91.3)		 60.0
(36.4, 80.0)		 0.70
(0.53, 0.86)		 67.3 65.3
NIER 0.12 93.1
(75.8, 98.8)		 75.0
(50.6, 90.4)		 0.86
(0.75, 0.97)		 71.4 71.4
NDER 0.41 89.7
(71.5, 97.3)		 60.0
(36.4, 80)		 0.79
(0.67, 0.92)		 69.4 69.4
NMTR +
NIER		 0.43 93.1
(75.8, 98.8)		 80.0
(55.7, 93.4)		 0.88
(0.78, 0.99)		 83.7 83.7

Abbreviations: AUC, area-under-the-curve; CI, confidence interval; NMTR, normalized magnetization transfer ratio; NIER, normalized initial enhancement ratio; NDER, normalized delayed enhancement ratio