Table 3.
Comparison of expected and observed frequencies of fractures according to NOF thresholds.
| Hip fracture | MOP fracture | |||
|---|---|---|---|---|
|
| ||||
| FRAX+BMD | FRAX-BMD | FRAX+BMD | FRAX-BMD | |
| Obese | ||||
| High risk | 24/38 | 32/43 | 51/51 | 58/54 |
| Low risk | 9/22 | 11/19 | 107/106 | 115/113 |
| PPV | 0.12 | 0.09 | 0.26 | 0.30 |
| NPV | 0.97 | 0.97 | 0.88 | 0.87 |
| Sensitivity | 0.63 | 0.69 | 0.32 | 0.31 |
| Specificity | 0.72 | 0.59 | 0.88 | 0.87 |
| Non-obese | ||||
| High risk | 258/341 | 350/374 | 495/445 | 617/492 |
| Low risk | 33/59 | 30/44 | 419/398 | 411/386 |
| PPV | 0.13 | 0.10 | 0.30 | 0.26 |
| NPV | 0.97 | 0.97 | 0.87 | 0.86 |
| Sensitivity | 0.85 | 0.89 | 0.53 | 0.56 |
| Specificity | 0.47 | 0.31 | 0.71 | 0.63 |
The figures are shown as predicted counts/observed counts
For hip fracture high risk is classified as a 10-yr fracture probability ≥ 3%
For MOP fracture high risk is classified as a 10-yr fracture probability ≥ 20%
NPV – negative predictive value; PPV – positive predictive value