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Illustration of toolkits to obtain RNA nanoparticles. (a) pRNA extended interlocking loop–loop interaction ‘hand-in-hand’, toolkit no. 1; (b) pRNA interaction via a palindrome sequence introduced at the 3′-end ‘foot-to-foot’, toolkit no. 2; and (c) 3WJ motif of pRNA 3WJ used to construct branched RNA nanoparticles, toolkit no. 3 [87]. (Adapted from [87]. © 2013 with permission from Cold Spring Harbor Laboratory Press.)
