Table 2. Total binding volumes of distribution (VT/fP) in the brain regions of interest for non-smokers and smokers (and the non-menthol smoker and menthol smoker subgroups).
Brain region | VT/fP values – non-smokers (n=51) | VT/fP values – smokers (n=63) | VT/fP values – non-menthol smoker subgroup (n=41) | VT/fP values – menthol smoker subgroup (n=22) |
---|---|---|---|---|
Thalamus | 16.0 (±3.6) | 16.3 (±3.1) | 15.7 (±2.8) | 17.3 (±3.4) |
Prefrontal cortex | 7.1 (±1.4) | 8.1 (±1.4)*** | 7.9 (±1.2)** | 8.6 (±1.6)*** |
Brainstem | 9.6 (±2.1) | 11.6 (±2.2)*** | 11.1 (±1.7)*** | 12.7 (±2.6)*** |
Cerebellum | 8.2 (±1.8) | 9.9 (±1.8)*** | 9.4 (±1.5)** | 10.8 (±2.1)*** |
Corpus callosum | 6.0 (±1.6) | 7.0 (±1.4)*** | 6.6 (±1.2)* | 7.6 (±1.6)*** |
p≤0.05,
p≤0.005,
p≤0.0005, compared to non-smokers (uncorrected).
All values are mean±s.d.