Table 2. P-values of the significance test testing the difference of the AUC ROC values between each pair of prediction methods.

Method	Biehl et al.	Vilar	Mean/LR-LASSO	EDF-MSE/LR-LASSO	Mean/LDA
Biehl et al.	–	–	–	–	–
Vilar	0.1598	–	–	–	–
Mean/LR-LASSO	0.1537	0.6809	–	–	–
EDF-MSE/LR-LASSO	0.2509	0.3486	0.6509	–	–
Mean/LDA	0.0003	0.0004	0.0019	0.0040	–

The null hypothesis is that the AUC ROC values between two methods are the same. Given p-values are provided by the online ROC analysis tool StAR [14].