Figure 2. Effects of bevacizumab on liver function in fibrotic rats.
The liver tissue and serum of the rats in each group was collected for assessment of liver function. GS, ALB, TB, AST and ALT were examined to assess hepatic function. Shown as the first two panels, GS and ALB levels were significantly lower of CCl4 group than that of normal control group. Bevacizumab administration significantly promoted synthesis of GS and ALB than that of CCl4 group. According to the left three panels, there were significantly differences of TB,ALT and AST levels among three groups. (*P<0.05).