Figure 7. hHSJ1a alters ubiquitylation in SOD1G93A spinal cord.
(A) Immunohistochemistry with SEDI anti-SOD1 antibody on 120 day lumbar spinal cord from female mice showed no reactivity in WT tissue and punctate staining in G93A and DBLE. Scale bar 50 µm (B) Immunofluorescence of G93A or DBLE 90 day spinal cord from female mice, as indicated, showed enhanced ubiquitin staining (green) in motor neuron cell bodies and processes labelled with βIII tubulin antibody (red). Nuclei were stained with DAPI visible in MERGE panel. Scale bar 20 µm.