Table 1. Examination of publicly available mass screening data reveals alterations in expression levels of commonly used “loading control” proteins.
| Protein Name | Symbol | Protein ID | Localisation | Alteration | Model | Tissue | Technique | Reference |
| Actin | Actc1 | IPI00654242.1 | Cytoskeleton | Upregulated (3.07 fold) | SMA mouse | Cardiac Muscle | Label Free Proteomics | Mutsaers et al 2011 [6] |
| Actin | Acta1 | IPI00110850.1 | Cytoskeleton | Upregulated (3.01 fold) | SMA mouse | Skeletal Muscle | Label Free Proteomics | Mutsaers et al 2011 [6] |
| Actin (Unspecified Isoform) | - | p60710 | Cytoskeleton | Absent | Wlds mouse | Striatal Synapses | 2D Gel Proteomics | Wishart et al 2007 [10] |
| actinin, alpha 1 | Actn1 | Q7TPR4 | Cytoskeleton | Downregulated (0.6 ratio) | SOD1 mouse | Cortical Synapses | iTRAQ Proteomics | Flynn et al 2012 [11] |
| Histone Cluster 1 | HC1 | NP_056601 | Nuclear | Upregulated (1.3 ratio) | AOPE mouse | Sciatic Nerve | iTRAQ Proteomics | Comely et al 2011 [12] |
| Tubulin Alpha 1B Chain | ActA1B | IPI00117348.4 | Cytoskeleton | Upregulated (1.32 fold) | SMA mouse | Skeletal Muscle | Label Free Proteomics | Mutsaers et al 2011 [6] |
| Tubulin Beta 4 Chain | TubB4 | IPI00109073.5 | Cytoskeleton | Downregulated (−1.16 ratio) | SMA mouse | Hippocampus | iTRAQ Proteomics | Wishart et al 2010 [13] |
| Tubulin beta-4 chain | Tubb4 | N/A | Cytoskeleton | Downregulated (−0.28 ratio) | Ercc1 mouse | Hippocampal synapses | iTRAQ Proteomics | Vegh et al 2012 [14] |
| tubulin, alpha 4a | TubA4A | P68366 | Cytoskeleton | Downregulated (−1.13 fold) | FTLD patient | Cerebellum | Gel Separation & Label free | de-Souza et al 2012 [15] |
| tubulin, beta 2a | Tubb2A | Q9CWF2 | Cytoskeleton | Upnregulated (0.26 ratio) | SOD1 mouse | Cortical Synapses | iTRAQ Proteomics | Flynn et al 2012 [11] |
| tubulin, beta 2a | Tubb2A | Q9CWF2 | Cytoskeleton | Upregulated (0.26 ratio) | FTLD patient | Prefrontal Cortex | Gel Separation & Label free | de-Souza et al 2012 [15] |
| Voltage Dependant anion Channel 1 | VDAC1 | q60932 | Mitochondrial | Downregulated (−4.08 fold) | Wlds mouse | Striatal Synapses | 2D Gel Proteomics | Wishart et al 2007 [10] |
| Voltage Dependant anion Channel 1 | VDAC1 | q60932 | Mitochondrial | Upregulated (96.4%) | PPT1 mouse | Cortex | Quantitative Western Blot | Kielar et al 2009 [16] |
| Voltage Dependant anion Channel 1 | VDAC1 | q60932 | Mitochondrial | Downregulated (−0.43 ratio) | SOD1 mouse | Cortical Synapses | iTRAQ Proteomics | Flynn et al 2012 [11] |
Note: Alterations listed in table are in units published in the original manuscript or accompanying supplementary material.