Table 1. Tumor cell line characteristics.

			CDH1 status, cell line			CDH1 status,
cell line	origin	established	nucleotide	meth.	protein	primary	ref.
IPH-926	ILBC1	2006	241ins4 (homo)	neg	neg	241ins4 (homo)	[20]–[22]
MDA-MB-134	ILBC2	1973	688del145 (homo)	neg	neg	na	[23]–[25]
SUM-44-PE	ILBC2	1993	1269delT (homo)	neg	neg	na	[5]; [26]
MDA-MB-435/M14	melanoma	1976	wt	pos	neg	na	[37]–[39]
BT-549	PABC	1978	wt	pos	neg	na	[36]; [37]

¹origin from ILBC proven by genetic comparison with the corresponding primary ILBC.

²origin from ILBC proposed ex post based on molecular features, corresponding primary tumor remained uncharacterized ILBC; infiltrating lobular breast cancer, PABC; papillary breast cancer, homo; homozygous, meth.; aberrant methylation of the CDH1 promoter, neg; negative, pos; positive, na; not assessed.