Table 1. Body weight and laboratory data from control, untreated and insulin-treated STZ-induced diabetic rats at the end of the study.
Control | Untreated STZ-induced diabetic rats | Insulin-treated STZ-induced diabetic rats | |
N | 12 | 10 | 10 |
Body weight (g) | 467±10 | 339±13§ | 349±4§ |
A1c (%) | 3.3±0.1 | 7.8±0.1§ | 8.1±0.2§ |
Insulin (ng/ml) | 2.03±0.51 | 0.17±0.03‡ | 0.34±0.05† |
Adiponectin (µg/ml) | 4.4±0.4 | 2.5±0.2‡ | 3.1±0.2* |
Leptin (ng/ml) | 7.2±1.2 | 0.6±0.1§ | 1.1±0.2§ |
T-chol (mg/dl) | 84.3±3.4 | 98.5±5.0* | 94.3±3.7 |
Free fatty acid (µEq/l) | 701±38 | 978±54† | 807±74** |
Data are means ± SE. * p<0.05, † p<0.005, ‡ p<0.0005, and § p<0.0001 vs. control rats; and ** p<0.05 vs. untreated STZ rats. T-chol: total cholesterol.