Table 2. Morphometric findings of sural nerves from control, untreated and insulin-treated STZ-induced diabetic rats.
Control | Untreated STZ-induced diabetic rats | Insulin-treated STZ-induced diabetic rats | |
N | 12 | 10 | 10 |
Fascicular area (mm2) | 0.071±0.004 | 0.070±0.003 | 0.076±0.002 |
MFD (103/mm2) | 15.0±0.5 | 15.3±0.6 | 14.6±0.6 |
Myelinated fiber area (µm2) | 39.2±0.9 | 39.1±1.2 | 38.5±1.5 |
Axonal area (µm2) | 19.0±0.4 | 18.9±0.6 | 18.8±0.9 |
Axon/myelin ratio | 1.01±0.02 | 0.98±0.02 | 1.00±0.03 |
Data are means ± SE. Intact myelinated fibers were morphometrically analysed. MFD: myelinated fiber density.