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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Obesity (Silver Spring). 2013 Jun 13;22(1):178–187. doi: 10.1002/oby.20465

Figure 6.

Figure 6

MnTBAP treatment failed to improve insulin resistance caused by HF feeding. (a) Fasting glucose and (b) fasting insulin levels measured at baseline and after glucose challenge during glucose tolerance tests. (c) Oxygen consumption of saponin-permeabilized soleus muscle fibers in the presence of succinate (5 mmol/L) and rotenone (10 μmol/L) (V0), after addition of 1 mmol/L ADP (VADP) and after inhibition of ATP synthase with 1μg/L oligomycin (Voligo). RCR is the respiratory control ratio of VADP/Voligo. (d) ATP/O ratios obtained by dividing ATP synthesis rates over VADP. Data are mean ± SEM; n=14-17 mice per group for (a) and n=7-17 mice per group for (b); n=5-8 mice per group for (c) and (d). * P < 0.05; ** P < 0.005 vs NC of the same treatment.