Table 1. Characteristicsa of nonmyeloablative hematopoietic cell transplant (HCT) recipients.
Characteristic | No. of patients |
---|---|
Total no. of patients | 84 |
Age (years) | 61.7 (20.0-73.1) |
Male | 52 (62%) |
Cancer diagnosis | |
Non-Hodgkin lymphoma | 28 (33%) |
Chronic lymphocytic leukemia | 16 (19%) |
Acute myeloid leukemia | 12 (14%) |
Multiple myeloma | 8 (10%) |
Myelodysplastic syndrome | 7 (8%) |
Myeloproliferative disorders | 4 (5%) |
Acute lymphocytic leukemia | 3 (4%) |
Other | 6 (7%) |
HCT comborbidity indexb | |
0 | 8 (10%) |
1 – 2 | 13 (15%) |
3 – 4 | 31 (37%) |
≥ 5 | 30 (36%) |
End organ dysfunctionc | |
Renal dysfunction d | 11 (13%) |
Liver dysfunctione | 12 (14%) |
Postgrafting immunosuppression concomitant with MMF | |
Cyclosporine | 58 (69%) |
Tacrolimus | 26 (31%) |
Sirolimus and calcineurin inhibitor | 13 (15%) |
aCategorical data presented as number of participants meeting stated criteria; continuous data presented as median (min-max); bHCT-Comorbidity index was assigned to 82 patients; c1 patient, included in both values below, had both renal and liver dysfunction; dcreatinine clearance < 60 ml/min, calculated with Cockroft Gault equation using actual body weight; etotal bilirubin > than 2 times laboratory upper normal limits, alanine aminotransferase or aspartate aminotransferase > than 3 times laboratory upper normal limits.