Table 2.
Genotype Distribution
| Genotype |
||||
|---|---|---|---|---|
| Gene and SNPs | Homozygous wild-type | Homozygous variant | Heterozygous | HW p value |
| Endothelin-1 | ||||
| rs5370 | 145 (G/G) | 14 (T/T) | 74 (G/T) | .257 |
| rs2071943 | 144 (G/G) | 16 (A/A) | 73 (A/G) | .111 |
| rs1626492 | 114 (G/G) | 12 (A/A) | 107 (A/G) | <.001* |
| rs5369 | 174 (G/G) | 5 (A/A) | 54 (A/G) | .769 |
| rs1476046 | 138 (G/G) | 15 (A/A) | 79 (A/G) | .265 |
| rs2070699 | 72 (G/G) | 45 (T/T) | 117 (G/T) | .944 |
| rs6912834 | 182 (A/A) | 2 (G/G) | 49 (G/T) | .410 |
| rs3087459 | 153 (A/A) | 5 (C/C) | 75 (A/C) | .294 |
| rs1800541 | 154 (T/T) | 5 (G/G) | 73 (G/T) | .357 |
| Endothelin receptor Type A | ||||
| rs6841799 | 115 (C/C) | 14 (G/G) | 100 (C/G) | .239 |
| rs5342 | 90 (A/A) | 30 (G/G) | 111 (A/G) | .695 |
| rs10305860 | 112 (G/G) | 14 (A/A) | 102 (A/G) | .106 |
| rs6537484 | 85 (C/C) | 25 (G/G) | 116 (C/G) | .081 |
| rs6812093 | 115 (A/A) | 14 (T/T) | 102 (A/T) | .195 |
| rs10008744 | 126 (A/A) | 11 (C/C) | 91 (A/C) | .345 |
| Endothelin receptor Type B | ||||
| rs9574124 | 114 (C/C) | 24 (C/G) | 93 (G/G) | .678 |
| rs4885493 | 129 (C/C) | 14 (G/G) | 73 (C/G) | .457 |
| rs4885491 | 171 (G/G) | 3 (A/A) | 48 (A/G) | .767 |
| rs3027111 | 154 (C/C) | 5 (T/T) | 61 (C/T) | .599 |
Note. HW = Hardy Weinberg equilibrium.
*
Significant (i.e., not in Hardy Weinberg equilibrium).