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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Cell Biochem Biophys. 2013 Sep;67(1):3–13. doi: 10.1007/s12013-013-9623-7

Figure 1. Intracellular proteolytic systems cross-talk.

Figure 1

Recent studies support many levels of functional interaction and cross-talk among the main proteolytic systems in the cell: the ubiquitin proteasome system (UPS) and the different autophagic pathways (macroautophagy, microautophagy and chaperone-mediated autophagy (CMA)). Some of the already identified levels of cross-talk are highlighted and discussed in the text.