Skip to main content
. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Int J Radiat Biol. 2009 Jun;85(6):523–531. doi: 10.1080/09553000902883810

Figure 1.

Figure 1

Clonogenic survival of FANCD2-deficient and wild-type complemented fibroblasts (PD20, filled symbols, and PD20-wtD2, open symbols, respectively). (A) Survival of adherent cells exposed to the indicated doses in air. (B) Survival of cell suspensions following a 1-hour incubation in air and 5% CO2 (see Methods and materials). (C) Survival of cells following exposure to 1–3 hours of anoxia, followed by plating for colony formation at room air (i.e., reoxygenation). Data points represent means +/− standard error based on at least three independent repeats with all gassing and irradiation carried out at room temperature. Radiation survival curves were fitted using the linear-quadratic formula and statistical comparisons between curves were carried out by use of the F test (two-sided) (GraphPad Prism 4.03, GraphPad Software, San Diego, CA, USA). Statistical significance was defined at the level of p = 0.05 or less.